Gavrilov N, Petkov P, Mermerski K
Arch Exp Veterinarmed. 1980;34(1):73-8.
Lapinised vaccine, strain "C", was used on 3500 fattening pigs on two farms in experiments for aerogenic immunisation. Two ordinary pigsties were modified for use as aerosol application chambers. A USSR-made disc-type aerosol generator, DAG-2, was used for vaccine dispersion. Piglets were allowed to be in contact with the aerosolic vaccine antigen for about 60 minutes. No deterioration in general health condition was observed, when longer contact periods were allowed. Existing respiratory disorders did not aggravate. Immunity was obtained seven or eight days from the time of aerosolic immunisation and lasted not less than ten months. The prospects of such groupwise immunisation of pigs against swine fever under conditions of industrialised rearing are discussed against the background of epizootiological and economic aspects. The results so far obtained from aerogenic immunisation form a good basis for its further development and eventual use under conditions of industrialised swine keeping.
兔化疫苗毒株“C”在两个农场的3500头育肥猪上用于气雾免疫实验。将两个普通猪舍改造为气雾应用室。使用苏联制造的圆盘式气雾发生器DAG - 2进行疫苗分散。仔猪与气雾疫苗抗原接触约60分钟。当允许更长的接触时间时,未观察到总体健康状况恶化。现有的呼吸道疾病也未加重。气雾免疫后7至8天获得免疫力,且持续不少于10个月。在流行病学和经济方面的背景下,讨论了在工业化饲养条件下对猪进行此类群体免疫预防猪瘟的前景。迄今为止从气雾免疫获得的结果为其进一步发展以及最终在工业化养猪条件下的应用奠定了良好基础。