Milev N, Gergov P, Peev Ia, Aleksandrov M, Chenchev I
Vet Med Nauki. 1987;24(4):7-12.
Attempts were made to immunize suckling pigs against classic swine fever. The pigs were treated orally, originating from sows which were immunized on the 30th-40th and the 90th-100th day of pregnancy, as well as from sows which were vaccinated one month prior to impregnation. A Bulgarian lapinized K vaccine and a Soviet LK-VNIIVViM cell culture were used (immunization being carried out 1-2 hours before the newborns were allowed to suck) at the rate of 150 doses for both vaccines. It was demonstrated that the application of a live vaccine, which was patterned as cited above, eliminated the inhibiting action of colostral antibodies and induced stable postvaccinal immunity. However, the effectiveness of the immunity conferred depended on the vaccine used in each specific case. The Soviet vaccine, in which the amount of the virus per vaccinal dose was five times as much, was shown to be more appropriate to the needs for oral immunization of suckling pigs of sows that were immune to classic swine fever than the lapinized K vaccine.
曾尝试对哺乳仔猪进行经典猪瘟免疫。这些仔猪口服给药，其母猪在怀孕第30 - 40天和第90 - 100天进行了免疫，还有一些母猪在受孕前一个月接种了疫苗。使用了保加利亚兔化K疫苗和苏联LK - VNIIVViM细胞培养物（在新生仔猪允许吮乳前1 - 2小时进行免疫），两种疫苗的用量均为150剂。结果表明，按上述方式使用活疫苗，消除了初乳抗体的抑制作用，并诱导了稳定的疫苗后免疫力。然而，所赋予免疫力的有效性取决于每个具体案例中使用的疫苗。每剂疫苗中病毒量为五倍的苏联疫苗，相较于兔化K疫苗，对免疫经典猪瘟的母猪所产哺乳仔猪进行口服免疫的需求而言，显得更为合适。
