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培养中的小鼠淋巴瘤L5178Y细胞在不同生长阶段的核仁。

The nucleolus in various phases of growth of mouse lymphoma L5178Y cells in culture.

作者信息

Kopeć J, Malec J, Sitarska E

出版信息

Arch Immunol Ther Exp (Warsz). 1980;28(1):145-51.

PMID:7416918
Abstract

The number of nucleoli in cultures of murine lymphoblasts L5178Y was investigated. It was found that during the cell cycle the number of nucleoli changed significantly. Comparison of the course of the cell cycle phases measured by the rate of 3H-thymidine incorporation into DNA and the mitotic index suggests that lymphoblasts containing 2 nucleoli are characteristic of the peak of the S-phase, lymphoblasts with 1 nucleolus--for the G1 phase or the border G1/S, lymphoblasts with 3 or more nucleoli--for the phase preceding mitosis, presumably late S and G2.

摘要

对小鼠成淋巴细胞L5178Y培养物中的核仁数量进行了研究。发现细胞周期中核仁数量有显著变化。通过将3H-胸腺嘧啶核苷掺入DNA的速率和有丝分裂指数测量的细胞周期各阶段进程进行比较表明,含有2个核仁的成淋巴细胞是S期高峰的特征,含有1个核仁的成淋巴细胞——处于G1期或G1/S边界,含有3个或更多核仁的成淋巴细胞——处于有丝分裂前阶段,推测为S期末期和G2期。

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