Krebber H J, Hill J D, Osborn J J, Iatridis A, Gerbode F
Artif Organs. 1980 Aug;4(3):167-70. doi: 10.1111/j.1525-1594.1980.tb03928.x.
This study has demonstrated that best results are achieved when the arterial line filter and the coronary suction line filter and combined. The arterial line filter should not be used alone, as it does not replace the coronary suction line filter. Different flow patterns enable the coronary suction line filter to hold most of the very small particles, while those pass the arterial line filter easily. No significant differences could be demonstrated in the number of circulating cellular elements of the blood with one or more filters in place. However, during the second half of the extracorporeal circulation, up to 50% of the small particles disappear in the patient, although there is no difference between the number infused into the patient and the number found in the venous blood during the first 30 to 45 minutes of bypass.
本研究表明,将动脉管路过滤器和冠状动脉吸引管路过滤器组合使用时可获得最佳效果。动脉管路过滤器不应单独使用,因为它不能替代冠状动脉吸引管路过滤器。不同的血流模式使冠状动脉吸引管路过滤器能够截留大部分非常小的颗粒,而这些颗粒能轻易通过动脉管路过滤器。在使用一个或多个过滤器的情况下,血液中循环细胞成分的数量未显示出显著差异。然而,在体外循环的后半段,尽管在体外循环开始的30至45分钟内注入患者体内的颗粒数量与在静脉血中发现的颗粒数量没有差异,但仍有高达50%的小颗粒在患者体内消失。