Liesegang T J, Campbell R J
Arch Ophthalmol. 1980 Aug;98(8):1385-9. doi: 10.1001/archopht.1980.01020040237004.
One hundred twenty-six surgically excised pigmented lesions of the conjunctiva were evaluated and correlated with clinical data and follow-up information. Of these, 42 were classified as conjunctival melanomas, with 18 arising apparently de novo, 15 from acquired melanosis, and nine from nevi. The six tumor deaths occurred only in patients with melanomas arising de novo or from acquired melanosis, Patients with tumor deaths usually demonstrated local recurrences long before metastases occurred. Moreover, several patients had local recurrences treated repeatedly for years without metastatic spread. Recent clinical findings relating to skin melanomas were applied and evaluated.
对126例手术切除的结膜色素沉着病变进行了评估，并与临床数据和随访信息进行了关联分析。其中，42例被分类为结膜黑色素瘤，18例明显为原发性，15例由获得性黑色素沉着症引起，9例由痣引起。6例肿瘤死亡仅发生在原发性或由获得性黑色素沉着症引起的黑色素瘤患者中。肿瘤死亡患者通常在转移发生前很久就出现局部复发。此外，有几位患者的局部复发经过多年反复治疗但未发生转移扩散。应用并评估了与皮肤黑色素瘤相关的最新临床研究结果。
