Regrowth of olfactory sensory axons into transplanted neural tissue. 1. Development of connections with the occipital cortex.

Presumptive occipital cortex was transplanted from 15-day-old embryos to host mice 10 days of age close to the ethmoidal lamina cribrosa, previous to partial or total bulbectomy of the host. The transplants have been studied for a period up to 150 days on histological preparations stained with iron hematoxylin and Bodian methods. The olfactory sensory axons, which degenerate as a result of bulbectomy, subsequently regenerate and invade the transplant, where they form characteristic glomerular structures. The transplant's neurons show interesting relations with the newly formed glomeruli. Significance of the results is briefly discussed.