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白化大鼠脑电图中的自发性全身性棘波放电。

Spontaneous generalized spike-wave discharges in the electrocorticograms of albino rats.

作者信息

Robinson P F, Gilmore S A

出版信息

Brain Res. 1980 Nov 17;201(2):452-8. doi: 10.1016/0006-8993(80)91052-5.

DOI:10.1016/0006-8993(80)91052-5
PMID:7417856
Abstract

Generalized epileptiform discharges occur spontaneously in the electrocorticograms of some albino laboratory rats. These discharges occur during periods of quiet wakefulness, are composed of 6-10/sec spike-wave complexes, are accompanied by locomotor arrest and often by mild clonic facial movements. The occurrence of these discharges is unrelated to surgical procedures used to create chronic recording preparations. Similar discharges and behavior have been induced in controls by injections of pentylenetetrazol.

摘要

在一些白化实验大鼠的皮质电图中会自发出现全身性癫痫样放电。这些放电出现在安静觉醒期,由每秒6 - 10次的棘慢复合波组成,伴有运动停止,且常伴有轻微的面部阵挛性运动。这些放电的出现与用于制作慢性记录准备的外科手术无关。通过注射戊四氮,在对照动物中也诱发了类似的放电和行为。

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