John H A, Lawson H
Cell Biol Int Rep. 1980 Sep;4(9):841-50. doi: 10.1016/0309-1651(80)90182-4.
The effect of different collagen types prepared from muscle used as substrata on myogenesis in tissue culture was investigated. Myogenic cells cultured on type I collagen aligned in parallel in some regions of the culture dish and single myotubes could extend for several centimetres. Myotubes grown on type V collagen did not have a normal elongated appearance and were not aligned.
研究了从肌肉制备的不同类型胶原蛋白作为底物对组织培养中肌发生的影响。在I型胶原蛋白上培养的成肌细胞在培养皿的某些区域平行排列,单个肌管可以延伸数厘米。在V型胶原蛋白上生长的肌管没有正常的伸长外观,也没有排列整齐。