Felberg N T, Donoso L A
Invest Ophthalmol Vis Sci. 1980 Oct;19(10):1242-5.
Surface and cytoplasmic antigens in retinoblastoma were examined by antisera prepared against two tissue-cultured retinoblastoma cell lines. In addition, several other antisera, including anti-rhodopsin, anti-rod outer segment, anti-large-molecular-weight protein, anti-S, and anti-P antigen, were also utilized in a complement-dependent cytotoxicity assay in order to explore the tumor cell surface. Antisera to tissue-cultured retinoblastoma cell lines were cross-reactive to both cell lines as was rod outer segment antiserum.
利用针对两种组织培养的视网膜母细胞瘤细胞系制备的抗血清检测视网膜母细胞瘤中的表面抗原和细胞质抗原。此外，还使用了其他几种抗血清，包括抗视紫红质、抗视杆细胞外段、抗大分子蛋白、抗S和抗P抗原，进行补体依赖性细胞毒性试验，以探究肿瘤细胞表面。针对组织培养的视网膜母细胞瘤细胞系的抗血清与这两种细胞系以及视杆细胞外段抗血清均有交叉反应。
