• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Hanganutziu-Deicher heterophile antigen in human retinoblastoma cells.

作者信息

Ohashi Y, Sasabe T, Nishida T, Nishi Y, Higashi H

出版信息

Am J Ophthalmol. 1983 Sep;96(3):321-5. doi: 10.1016/s0002-9394(14)77822-5.

DOI:10.1016/s0002-9394(14)77822-5
PMID:6351622
Abstract

We investigated the possible existence of Hanganutziu-Deicher antigen (HD antigen) on retinoblastoma cells by means of indirect membrane immunofluorescence and a complement-dependent antibody-mediated cytotoxicity test. We prepared antiserum in the chicken by immunization with purified equine hematoside highly specific to HD antigen. Three kinds of retinoblastoma cell lines, Y-79, WERI-Rb 1, and TOTL-1, showed positive membrane staining. Y-79 and TOTL-1 cells were also confirmed by the cytotoxicity test to possess HD antigen. Retinoblastoma cells freshly isolated from two patients had a positive membrane immunofluorescence. These results indicated that HD antigen was expressed in human retinoblastoma cells in vitro as well as in vivo.

摘要

相似文献

1
Hanganutziu-Deicher heterophile antigen in human retinoblastoma cells.
Am J Ophthalmol. 1983 Sep;96(3):321-5. doi: 10.1016/s0002-9394(14)77822-5.
2
Detection of gangliosides as N-glycolylneuraminic acid-specific tumor-associated Hanganutziu-Deicher antigen in human retinoblastoma cells.在人视网膜母细胞瘤细胞中检测神经节苷脂作为N-羟乙酰神经氨酸特异性肿瘤相关的汉努齐乌-戴歇尔抗原。
Jpn J Cancer Res. 1988 Aug;79(8):952-6. doi: 10.1111/j.1349-7006.1988.tb00060.x.
3
Hanganutziu and Deicher type heterophile antigen expressed on the cell surface of Marek's disease lymphoma-derived cell lines.马立克氏病淋巴瘤来源的细胞系细胞表面表达的汉氏（Hanganutziu）和戴氏（Deicher）嗜异性抗原
Biken J. 1981 Jun;24(1-2):23-37.
4
Hanganutziu-Deicher type-heterophile antigen-positive cells in human cancer tissues demonstrated by membrane immunofluorescence.
Biken J. 1982 Mar;25(1):47-50.
5
Tumor-associated expression of glycosphingolipid Hanganutziu-Deicher antigen in human cancers.人类癌症中糖鞘脂类汉根纽茨尤-戴歇尔抗原的肿瘤相关表达。
Gan. 1984 Nov;75(11):1025-9.
6
Surface and cytoplasmic antigens in retinoblastoma.视网膜母细胞瘤中的表面抗原和细胞质抗原。
Invest Ophthalmol Vis Sci. 1980 Oct;19(10):1242-5.
7
Immunohistochemical detection of heterophile Hanganutziu-Deicher antigen in human malignant melanoma.人恶性黑色素瘤中嗜异性汉氏-戴氏抗原的免疫组织化学检测
Arch Dermatol Res. 1990;282(3):179-82. doi: 10.1007/BF00372619.
8
Analysis of the expression of Hanganutziu-Deicher (HD) antigen in human malignant melanoma.人类恶性黑色素瘤中汉努齐乌-戴歇尔（HD）抗原表达的分析。
J Dermatol. 1992 Nov;19(11):827-30. doi: 10.1111/j.1346-8138.1992.tb03791.x.
9
Expression of heterophile, Paul-Bunnell and Hanganutziu-Deicher antigens on human melanoma cell lines.人黑色素瘤细胞系上嗜异性、保罗-邦内尔和汉加努齐乌-戴歇尔抗原的表达。
Int Arch Allergy Appl Immunol. 1987;83(2):160-6. doi: 10.1159/000234349.
10
Heterophile Hanganutziu-Deicher antigen in ganglioside fractions of human melanoma tissues.人黑色素瘤组织神经节苷脂组分中的嗜异性汉氏-戴氏抗原
Int Arch Allergy Appl Immunol. 1988;85(3):381-3. doi: 10.1159/000234536.

引用本文的文献

1
Development and applications of sialoglycan-recognizing probes (SGRPs) with defined specificities: exploring the dynamic mammalian sialoglycome.具有明确特异性的唾液酸糖识别探针 (SGRP) 的开发和应用：探索动态哺乳动物唾液酸糖组。
Glycobiology. 2022 Nov 22;32(12):1116-1136. doi: 10.1093/glycob/cwac050.
2
Antitumor effects of the GM3(Neu5Gc) ganglioside-specific humanized antibody 14F7hT against Cmah-transfected cancer cells.GM3(Neu5Gc)神经节苷脂特异性人源化抗体 14F7hT 对 Cmah 转染癌细胞的抗肿瘤作用。
Sci Rep. 2019 Jul 9;9(1):9921. doi: 10.1038/s41598-019-46148-1.
3
From "Serum Sickness" to "Xenosialitis": Past, Present, and Future Significance of the Non-human Sialic Acid Neu5Gc.
从“血清病”到“异嗜性唾液酸炎”：非人类唾液酸 Neu5Gc 的过去、现在和未来意义。
Front Immunol. 2019 Apr 17;10:807. doi: 10.3389/fimmu.2019.00807. eCollection 2019.
4
Involvement of a non-human sialic Acid in human cancer.一种非人类唾液酸在人类癌症中的作用。
Front Oncol. 2014 Feb 19;4:33. doi: 10.3389/fonc.2014.00033. eCollection 2014.
5
LC-MS analysis of polyclonal human anti-Neu5Gc xeno-autoantibodies immunoglobulin G Subclass and partial sequence using multistep intravenous immunoglobulin affinity purification and multienzymatic digestion.采用多步静脉注射免疫球蛋白亲和纯化和多酶消化法对多克隆人抗-Neu5Gc 异源自身抗体免疫球蛋白 G 亚类和部分序列进行 LC-MS 分析。
Anal Chem. 2012 Mar 20;84(6):2761-8. doi: 10.1021/ac2030893. Epub 2012 Feb 28.
6
Sensitive and specific detection of the non-human sialic Acid N-glycolylneuraminic acid in human tissues and biotherapeutic products.在人体组织和生物治疗产品中灵敏且特异的检测非人唾液酸N-羟乙酰神经氨酸。
PLoS One. 2009;4(1):e4241. doi: 10.1371/journal.pone.0004241. Epub 2009 Jan 21.
7
Evidence for a human-specific mechanism for diet and antibody-mediated inflammation in carcinoma progression.饮食和抗体介导的炎症在癌症进展中的人类特异性机制的证据。
Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18936-41. doi: 10.1073/pnas.0803943105. Epub 2008 Nov 18.
8
Loss of N-glycolylneuraminic acid in humans: Mechanisms, consequences, and implications for hominid evolution.人类中N-羟乙酰神经氨酸的缺失：机制、后果及其对灵长类动物进化的影响。
Am J Phys Anthropol. 2001;Suppl 33(Suppl):54-69. doi: 10.1002/ajpa.10018.abs.
9
A naturally occurring 46-amino acid deletion of cytidine monophospho-N-acetylneuraminic acid hydroxylase leads to a change in the intracellular distribution of the protein.胞苷单磷酸-N-乙酰神经氨酸羟化酶天然存在的46个氨基酸缺失导致该蛋白质细胞内分布的改变。
Glycoconj J. 1996 Jun;13(3):353-8. doi: 10.1007/BF00731467.
10
Establishment of a human monoclonal antibody to Hanganutziu-Deicher antigen as a tumor-associated carbohydrate antigen.建立一种针对汉努齐乌-戴歇尔抗原（一种肿瘤相关碳水化合物抗原）的人单克隆抗体。
Jpn J Cancer Res. 1988 Dec;79(12):1340-8. doi: 10.1111/j.1349-7006.1988.tb01565.x.