Tinnemans J G, Gerritsen S M
Intensive Care Med. 1980 Aug;6(4):211-3. doi: 10.1007/BF01687159.
A case is described of acute defibrination following blunt head injury in a patient with a Spitz-Holter drain. The cause of the disseminated intravascular coagulation is thought to be due to brain thromboplastins entering the systemic circulation through the Spitz-Holter drain, thus bypassing the blood-brain barrier.
