Brannan T S, Burger A A, Chaudhary M Y
J Neurol Neurosurg Psychiatry. 1980 May;43(5):403-6. doi: 10.1136/jnnp.43.5.403.
Thirty-eight cases of basal ganglia calcification imaged on computed axial tomography were reviewed. Most cases were felt to represent senescent calcification. The possibility of a vascular aetiology in this group is discussed. A less common group of patients was identified with calcification secondary to abnormalities in calcium metabolism or radiation therapy. Three cases of basal ganglia calcifications were detected in juvenile epileptic patients receiving chronic anticonvulsants. These cases may be related to abnormalities in calcium metabolism and alkaline phosphatase activity. Clinical evidence of basal ganglia abnormality was generally absent demonstrating the preservation of neuronal pathways in most cases.
回顾了38例经计算机断层扫描成像的基底节钙化病例。大多数病例被认为是老年性钙化。讨论了该组中血管病因的可能性。发现了一组不太常见的患者,其钙化继发于钙代谢异常或放射治疗。在接受慢性抗惊厥药物治疗的青少年癫痫患者中检测到3例基底节钙化。这些病例可能与钙代谢和碱性磷酸酶活性异常有关。基底节异常的临床证据通常不存在,表明大多数病例中神经通路得以保留。