Siccardi A G, Marconi M M, Ferrari F A, Fortunato A, Giannetti A, Sacchi F T, Beretta A, Ugazio A G, Jayakar S D
J Clin Lab Immunol. 1980 May;3(3):165-70.
Two separate functional defects of the alternate pathway of complement (defective yeast opsonisation and defective rabbit erythrocyte lysis) are very frequent (of the order of 55% for the former and 35% for the latter) among atopic children and their unaffected relatives. The defects are independent of each other and of sex, age, season of sampling, type of atopic syndrome and IgE level. The alternative pathway initiation mechanism is probably involved in both defects.
补体替代途径的两种独立功能缺陷（酵母调理作用缺陷和兔红细胞溶解缺陷）在特应性儿童及其未患病亲属中非常常见（前者约为55%，后者约为35%）。这些缺陷相互独立，且与性别、年龄、采样季节、特应性综合征类型和IgE水平无关。替代途径起始机制可能与这两种缺陷均有关。
