Schellhammer P F, Ladaga L E, El-Mahdi A
J Urol. 1980 May;123(5):700-5. doi: 10.1016/s0022-5347(17)56096-6.
There were 39 prostatic needle biopsies obtained from 33 patients with carcinoma of the prostate 1 to 3 years after definitive treatment with interstitial implantation using 125iodine radioactive sources. Of these biopsies 57 per cent obtained at 12 to 18 months and 73 per cent obtained at 19 to 36 months after implantation were negative for malignancy. All biopsies revealed histologic evidence of significant radiation injury. Neither the presence or absence of malignancy on biopsy nor the degree of radiation injury could be related to the initial stage and grade of the prostatic neoplasm.
对33例前列腺癌患者在使用¹²⁵碘放射性源进行间质植入根治性治疗后1至3年获取了39份前列腺穿刺活检标本。在这些活检标本中，植入后12至18个月获取的标本有57%、19至36个月获取的标本有73%未发现恶性肿瘤。所有活检均显示出明显放射性损伤的组织学证据。活检时是否存在恶性肿瘤以及放射性损伤程度均与前列腺肿瘤的初始分期和分级无关。
