Kandzari S J, Belis J A, Kim J C, Gnepp D R, Riley R S
J Urol. 1982 May;127(5):923-7. doi: 10.1016/s0022-5347(17)54133-6.
Eighty patients with clinically early stage adenocarcinoma of the prostate were treated with pelvic lymphadenectomy and interstitial implantation of 125iodine seeds. A new applicator that permits greater accuracy in spacing the seeds has been developed. Postoperative complications were minimal, with urinary irritability being the most common. Multiple transrectal needle biopsies were performed 12 and 18 months after treatment in 46 patients. The prostatic biopsies were negative for carcinoma in 61 per cent and positive in 39 per cent of the patients. Long-term followup is needed to correlate post-treatment biopsies with survival and to determine if patients with positive biopsies should receive further treatment.
80例临床早期前列腺腺癌患者接受了盆腔淋巴结清扫术和125碘粒子间质植入治疗。已研发出一种新的施源器，可在粒子间距方面实现更高的精准度。术后并发症极少，其中尿路刺激症状最为常见。46例患者在治疗后12个月和18个月时接受了多次经直肠穿刺活检。前列腺活检结果显示，61%的患者癌组织呈阴性，39%的患者呈阳性。需要进行长期随访，以将治疗后的活检结果与生存率相关联，并确定活检呈阳性的患者是否应接受进一步治疗。
