Milleman L A, Weissman W D, Culp D A
J Urol. 1980 May;123(5):710-11. doi: 10.1016/s0022-5347(17)56099-1.
Alterations in serum proteins, enzymes and immunoglobulins were analyzed sequentially in 40 patients undergoing perineal cryosurgery for carcinoma of the prostate. A search was made for evidence of a tumor marker and for augmented host response attributable to an immune mechanism. The data showed little evidence to support a systemic immune response. A reliable tumor marker could not be identified when cryosurgery was used alone.
对40例因前列腺癌接受会阴部冷冻手术的患者的血清蛋白、酶和免疫球蛋白变化进行了连续分析。研究了肿瘤标志物的证据以及归因于免疫机制的宿主反应增强的证据。数据显示几乎没有证据支持全身免疫反应。单独使用冷冻手术时，无法确定可靠的肿瘤标志物。
