Williams C
Plast Reconstr Surg. 1980 Sep;66(3):448-52.
We are reporting what we believe to be the second case of bilateral parotid neoplasm occuring synchronously with differing histologies. We believe that this neoplasm may represent a specific propensity of parotid tissue in a given individual to develop neoplasia in a multipotential glandular organ subject to many neoplastic diseases. There also exists the possibility that this condition may represent an immune deficiency specific to the parotid gland. The case reports that have been reviewed demonstrate that a secondary neoplasm may arise from benign mixed tumors. We question whether this is an example of monistic origin of acinic cell tumor from a mixed-cell tumor or, perhaps, dualistic expression for this salivary gland to develop a multiplicity of anaplastic and metaplastic growth variants. In approaching a case with bilateral parotid involvement, the physician must be aware of the rare possibility that benign and malignant tumors may coexist. He must be prepared to proceed with more radical extirpation than simple superficial parotidectomy.
我们报告了我们认为是第二例双侧腮腺肿瘤同时发生且组织学不同的病例。我们认为，这种肿瘤可能代表了特定个体腮腺组织在受多种肿瘤性疾病影响的多潜能腺器官中发生肿瘤形成的一种特殊倾向。也存在这种情况可能代表腮腺特异性免疫缺陷的可能性。已审查的病例报告表明，继发性肿瘤可能起源于良性混合瘤。我们质疑这是腺泡细胞肿瘤起源于混合细胞瘤的一元论例子，还是也许是该唾液腺发展出多种间变性和化生生长变体的二元论表现。在处理双侧腮腺受累的病例时，医生必须意识到良性和恶性肿瘤可能共存这种罕见的可能性。他必须准备好进行比单纯浅叶腮腺切除术更彻底的切除。
