高加索人群中人类近端着丝粒染色体RFA颜色多态性的频率：与QFQ多态性的相互关系。

Frequency of RFA colour polymorphisms of human acrocentric chromosomes in caucasians: interrelationship with QFQ polymorphisms.

作者信息

Verma R S, Dosik H, Lubs H A

出版信息

Ann Hum Genet. 1977 Oct;41(2):257-67. doi: 10.1111/j.1469-1809.1977.tb01922.x.

DOI:10.1111/j.1469-1809.1977.tb01922.x

Abstract

One hundred normal caucasians were studied by sequential QFQ and RFA in order to estimate the type and frequency of variation. Colour variants were classified into 1 of 6 colours by RFA and intensity variations into 1 of 5 levels by QFQ. The interrelationship between QFQ and RFA variants was also examined. It was found that there was no consistent relationship between negative or brilliant QFQ variants and the various colours observed with RFA. RFA colour polymorphisms for chromosomes 13, 14, 15, 21 and 22 were 33.0, 38.0, 28.0, 50.0 and 24.5% while QFQ frequencies were 56.5, 10.0, 10.0, 15.5 and 10.0% respectively. RFA is especially useful in studying the inheritance of chromosome 21.

摘要

为了评估变异的类型和频率，对100名正常白种人进行了连续的QFQ和RFA检测。通过RFA将颜色变异分为6种颜色中的1种，通过QFQ将强度变异分为5个等级中的1个。还研究了QFQ和RFA变异之间的相互关系。结果发现，QFQ阴性或明亮变异与RFA观察到的各种颜色之间没有一致的关系。13、14、15、21和22号染色体的RFA颜色多态性分别为33.0%、38.0%、28.0%、50.0%和24.5%，而QFQ频率分别为56.5%、10.0%、10.0%、15.5%和10.0%。RFA在研究21号染色体的遗传方面特别有用。