正常和动脉粥样硬化大鼠灌注离体后肢中前列腺素的释放
Prostaglandin release from perfused, isolated hind legs in normal and arteriosclerotic rats.
作者信息
Baraka Y M, Bekemeier H, Giessler A J, Rashid R
出版信息
Acta Biol Med Ger. 1978;37(5-6):851-3.
PMID:742301
Abstract
Intraarterial injection of 10 microgram noradrenaline (NA) produced a stronger increase of prostaglandin E-like material (PGE) in the outflow of isolated perfused hind legs of normal rats than of those of arteriosclerotic rats. The vasopressor effect of NA in normal rats was stronger than in arteriosclerotic rats, which could be explained on the basis of PGE release.
摘要
动脉内注射10微克去甲肾上腺素（NA）后，正常大鼠离体灌流后肢流出液中前列腺素E样物质（PGE）的增加幅度比动脉粥样硬化大鼠的更大。NA对正常大鼠的升压作用比对动脉粥样硬化大鼠更强，这可以基于PGE的释放来解释。
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