Levitt T A, Loring R H, Salpeter M M
Science. 1980 Oct 31;210(4469):550-1. doi: 10.1126/science.7423205.
The turnover rate of acetylcholine receptors at neuromuscular junctions in mice increases progressively after denervation and, after 15 days, reaches a half-time of 30 z 5 hours. Denervation thus causes the clustered junctional acetylcholine receptors to assume the rapid turnover characteristic of extrajunctional receptors before innervation.
小鼠神经肌肉接头处乙酰胆碱受体的周转率在去神经支配后逐渐增加，15天后达到30±5小时的半衰期。因此，去神经支配使聚集在接头处的乙酰胆碱受体呈现出神经支配前接头外受体的快速周转特征。
