I抗原与H抗原的关系。I. 对正常人群血浆和唾液的研究。

Relationship between I and H antigens. I. A study of the plasma and saliva of a normal population.

作者信息

Rouger P, Juszczak G, Doinel C, Salmon C

出版信息

Transfusion. 1980 Sep-Oct;20(5):536-9. doi: 10.1046/j.1537-2995.1980.20581034506.x.

DOI:10.1046/j.1537-2995.1980.20581034506.x

Abstract

The H and I antigens were studied in the plasma and saliva of 52 group O subjects, by hemagglutination inhibition at continuous flow. H plasma substance was detected with one anti-H antibody from a Bh donor. Secretors have more H plasma substance than do non-secretors, but there was no relationship between the amounts of I and H substances in the plasma. On the contrary, the amounts of I substance in the saliva detected by anti-I (Sti) is a function of secretor status. Nonsecretors had a much greater amount of I in saliva than did secretors. These results support the hypothesis that I antigen (detected by anti-I (Sti)) is a part of the substrate of H antigen.

摘要

通过连续流动血凝抑制法，对52名O型血受试者的血浆和唾液中的H抗原和I抗原进行了研究。用来自Bh供体的一种抗H抗体检测H血浆物质。分泌型个体比非分泌型个体具有更多的H血浆物质，但血浆中I物质和H物质的量之间没有关系。相反，用抗I（Sti）检测到的唾液中I物质的量是分泌型状态的函数。非分泌型个体唾液中的I物质比分泌型个体多得多。这些结果支持了I抗原（由抗I（Sti）检测）是H抗原底物一部分的假说。