Schenk J, Döbrönte Z, Koch H, Stolte M
Z Gastroenterol. 1980 Jul;18(7):389-94.
A 97% d-limonene preparation was injected as a bolus into the biliary tract of cats. Depending on volume, contact time, and flow direction of the solution, acute or chronic inflammatory damages for varions degrees were found in the hepatobiliary tissues of all animals treated with the d-limonene solution. These observed histopathological changes due to contact with the terpene compound, restrict the value of the d-limonene preparation as described by Igimi et al. for dissolving cholesterol gallstones retained in the human common bile duct.
将97%的d - 柠檬烯制剂作为大剂量注射剂注入猫的胆道。根据溶液的体积、接触时间和流动方向，在用d - 柠檬烯溶液处理的所有动物的肝胆组织中均发现了不同程度的急性或慢性炎性损伤。这些因与萜类化合物接触而观察到的组织病理学变化，限制了Igimi等人所描述的d - 柠檬烯制剂在溶解人类胆总管中滞留的胆固醇胆结石方面的价值。
