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[关于后路脊柱融合术后脊柱生长的实验研究(作者译)]

[Experimental investigations on the growth of the vertebral column after dorsal spondylodesis (author's transl)].

作者信息

Meznik F, Pflüger G, Plenk H, Fischerleitner F, Grundschober F, Machacek F

出版信息

Z Orthop Ihre Grenzgeb. 1980;118(1):28-40. doi: 10.1055/s-2008-1051468.

Abstract

To investigate the question which growth processes take place in dorsally stiffened vertebral regions, 4 vertebral segments each were dorsally fused in twenty-one pigs, using Harrington's distraction system in 20 cases. X-ray examination and histological measurements conducted with the aid of fluorochromosequential markings showed a more or less pronounced growth of the vertebral bodies and of the fusion mass in all animals. As a rule, the sequence of vertebral bodies overgrows the fusion mass in longitudinal direction, which always results in lordosis of the stiffened region. The longitudinal growth of the vertebral bodies, and even more so of the fusion mass, decreases with increasing postoperative observation time. The fusion mass shows actual internal growth which proceeds partly in diffuse manner in all directions, in the region of the clefts, i.e. as spondyloschisis, in some cases also in the same direction as with enchondral ossification associated with columnar chondrification. The growth of the fused mass does not depend on the formation of a pseudoarthrosis, although it is probably quantitatively promoted by pseudarthroses. The stimulus to longitudinal growth of the fused mass originates from the growing vertebral bodies, with probably varying influence of tensile and compressive forces.

摘要

为了研究在背侧僵硬的椎体区域发生哪些生长过程,在21头猪中,每头猪的4个椎体节段进行背侧融合,其中20例使用哈林顿撑开系统。借助荧光色素顺序标记进行的X线检查和组织学测量显示,所有动物的椎体和融合块均有或多或少明显的生长。通常,椎体序列在纵向方向上超过融合块,这总是导致僵硬区域的脊柱前凸。椎体的纵向生长,尤其是融合块的纵向生长,随着术后观察时间的增加而减少。融合块显示出实际的内部生长,部分在裂隙区域以向各个方向扩散的方式进行,即脊柱裂,在某些情况下,也与柱状软骨化相关的软骨内成骨方向相同。融合块的生长不依赖于假关节的形成,尽管假关节可能在数量上促进其生长。融合块纵向生长的刺激源自生长中的椎体,拉伸力和压缩力的影响可能各不相同。

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