[纹状体刺激以及微量离子电泳施加多巴胺和乙酰胆碱对苍白球神经元活动的影响]
[Effects of striatum stimulation and micro-iontophoretically applied dopamine and acetylcholine on the neuronal activity of the globus pallidus].
作者信息
Böttger G, Schmidt J
出版信息
Acta Biol Med Ger. 1980;39(1):123-31.
Alert, myorelaxed rats were used to study the influence of electrical stimulation of the stiatum and micro-iontophoretic application of dopamine and acetylcholine upon the discharge activity of neurons of the Globus pallidus. Out of 55 pallidal neurons, 25 responded to striatum stimulation with an initial inhibition and subsequent irritation, and 21 with an irritation-inhibition sequence. 40% of the neurons were dopamine-sensitive (23% irritation, 77% inhibition) and 38% choline-sensitive (63% inhibition, 37% irritation). 25% of the dopamine-sensitive neurons were at the same time choline-sensitive. There was no direct relation demonstrable between the effects of striatum stimulation and micro-iontophoretic application of acetylcholine or dopamine.
选用警觉、肌肉松弛的大鼠来研究纹状体电刺激以及多巴胺和乙酰胆碱的微离子透入对苍白球神经元放电活动的影响。在55个苍白球神经元中，25个对纹状体刺激的反应是先抑制后兴奋，21个的反应是先兴奋后抑制。40%的神经元对多巴胺敏感（23%兴奋，77%抑制），38%的神经元对胆碱敏感（63%抑制，37%兴奋）。25%对多巴胺敏感的神经元同时也对胆碱敏感。纹状体刺激的效应与乙酰胆碱或多巴胺的微离子透入之间未显示出直接关系。
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