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46,XY女性的恒牙大小。

Permanent tooth sizes in 46,XY females.

作者信息

Alvesalo L, Varrela J

出版信息

Am J Hum Genet. 1980 Sep;32(5):736-42.

PMID:7424913
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1686090/
Abstract

The teeth of seven Finnish patients with complete testicular-feminization syndrome (46,XY females) were studied to obtain further information about their growth and possible somatic determinants on the Y chromosome. The sizes of the permanent teeth of the 46,XY females were found to be as large as those of control males and definitely larger than those of control females. Testicular feminization is caused by androgen insensitivity, and persons affected are phenotypically females. Hence, these results also indicate the influence of the Y chromosome on dental determination.

摘要

对7名患有完全性睾丸女性化综合征(46,XY女性)的芬兰患者的牙齿进行了研究,以获取有关其生长以及Y染色体上可能的体细胞决定因素的更多信息。发现46,XY女性恒牙的大小与对照男性的恒牙大小一样大,并且肯定大于对照女性的恒牙大小。睾丸女性化是由雄激素不敏感引起的,受影响的个体在表型上为女性。因此,这些结果也表明了Y染色体对牙齿发育的影响。

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引用本文的文献

1
47,XXY males: sex chromosomes and tooth size.47,XXY男性:性染色体与牙齿大小。
Am J Hum Genet. 1980 Nov;32(6):955-9.
2
Enamel thickness of 45,X females' permanent teeth.45,X女性恒牙的牙釉质厚度
Am J Hum Genet. 1981 May;33(3):464-9.
3
The human enamel protein gene amelogenin is expressed from both the X and the Y chromosomes.人类牙釉质蛋白基因牙釉蛋白在X染色体和Y染色体上均有表达。
Am J Hum Genet. 1992 Feb;50(2):303-16.

本文引用的文献

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TIME OF ERUPTION OF THE PERMANENT TEETH, CEPHALOMETRIC AND TOOTH MEASUREMENT AND SULPHATION FACTOR ACTIVITY IN 45 PATIENTS WITH TURNER'S SYNDROME WITH DIFFERENT TYPES OF X CHROMOSOME ABERRATIONS.
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X-linked inheritance of developmental timing in man.
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Genes on the Y chromosome influencing rate of maturation in man: skeletal age studies in children with Klinefelter's (XXY) and Turner's (XO) syndromes.
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The influence of sex-chromosome genes on tooth size in man. A genetic and quantitative study.性染色体基因对人类牙齿大小的影响。一项遗传学和定量研究。
Suom Hammaslaak Toim. 1971;67(1):3-54.
6
Abnormalities of human sex chromosomes. I. A ring Y without mosaiciam.人类性染色体异常。I. 一条无嵌合体的Y环状染色体。
Ann Genet. 1973 Dec;16(4):225-31.
7
The 47,XYY male, Y chromosome, and tooth size.47,XYY男性、Y染色体与牙齿大小
Am J Hum Genet. 1975 Jan;27(1):53-61.
8
Sizes of deciduous teeth in 47,XYY males.47,XYY男性乳牙的大小
Am J Hum Genet. 1977 Sep;29(5):486-9.
9
Permanent tooth sizes in 46,XX-males.46,XX男性的恒牙大小。
Ann Hum Genet. 1979 Oct;43(2):97-102. doi: 10.1111/j.1469-1809.1979.tb02001.x.
10
Sexual differentiation and testosterone production.性别分化与睾酮生成
N Engl J Med. 1976 Oct 28;295(18):1011-2. doi: 10.1056/NEJM197610282951809.