Alvesalo L, Varrela J
Am J Hum Genet. 1980 Sep;32(5):736-42.
The teeth of seven Finnish patients with complete testicular-feminization syndrome (46,XY females) were studied to obtain further information about their growth and possible somatic determinants on the Y chromosome. The sizes of the permanent teeth of the 46,XY females were found to be as large as those of control males and definitely larger than those of control females. Testicular feminization is caused by androgen insensitivity, and persons affected are phenotypically females. Hence, these results also indicate the influence of the Y chromosome on dental determination.
对7名患有完全性睾丸女性化综合征(46,XY女性)的芬兰患者的牙齿进行了研究,以获取有关其生长以及Y染色体上可能的体细胞决定因素的更多信息。发现46,XY女性恒牙的大小与对照男性的恒牙大小一样大,并且肯定大于对照女性的恒牙大小。睾丸女性化是由雄激素不敏感引起的,受影响的个体在表型上为女性。因此,这些结果也表明了Y染色体对牙齿发育的影响。