Alvesalo L, Portin P
Am J Hum Genet. 1980 Nov;32(6):955-9.
Permanent tooth crowns of 47,XXY males were found to be generally larger than those of control males and females and their first-degree male and female relatives. These results suggest that tooth-size increase in 47,XXY males is due to a direct genetic effect and support the concept of the presence of a specific growth gene (or genes) in the human X and Y chromosomes. The effect of this gene (or genes) seems to be the promotion of tooth growth, and the Y chromosome is more effective than the X chromosome in this respect.
研究发现，47,XXY男性的恒牙牙冠通常比对照男性、女性以及他们的一级男性和女性亲属的恒牙牙冠更大。这些结果表明，47,XXY男性牙齿尺寸的增加是由于直接的遗传效应，支持了人类X和Y染色体中存在特定生长基因的概念。这种基因的作用似乎是促进牙齿生长，在这方面Y染色体比X染色体更有效。
