Hoogland H J, de Haan J, Martin C B
Am J Obstet Gynecol. 1980 Oct 15;138(4):441-3. doi: 10.1016/0002-9378(80)90143-x.
Placental growth during pregnancy was studied serially by ultrasonographic measurement of placental area in 50 primigravid women. Placental area at a menstrual age of 150 days was compared to infant birth weight. Small placental area at a menstrual age of 150 days was significantly related to low infant birth weight (< tenth percentile of birth weight for gestational age). A "warning limit" of placental area at midpregnancy was calculated. If placental area was equal to or smaller than this limit of 187 sq cm, six of nine patients (67%) compared to four of 41 subjects with larger placentas (p < 0.01) were delivered of a small-for-gestational age baby. Ultrasonographic placental area measurement in midpregnancy thus appears to be of prognostic value in identifying pregnancies at high risk for the subsequent occurrence of fetal growth.
通过超声测量50例初孕妇的胎盘面积，对孕期胎盘生长进行了连续研究。将月经龄150天时的胎盘面积与婴儿出生体重进行比较。月经龄150天时胎盘面积小与低出生体重婴儿（<胎龄出生体重的第十百分位数）显著相关。计算了孕中期胎盘面积的“警戒值”。如果胎盘面积等于或小于187平方厘米的这个值，9例患者中有6例（67%）分娩出小于胎龄儿，而胎盘较大的41例受试者中有4例（p<0.01）。因此，孕中期超声测量胎盘面积在识别随后发生胎儿生长高危妊娠方面似乎具有预后价值。
