Farr H W, Goldfarb P M, Farr C M
Am J Surg. 1980 Oct;140(4):563-7. doi: 10.1016/0002-9610(80)90213-5.
One thousand thirty-four cases of epidermoid carcinoma of the mouth and pharynx were seen by the Head and Neck Service of Memorial Hospital during a recent 5 year period, 1965 to 1969. The 656 determinate cases previously untreated offer a clear basis for evaluation of the 5 year results of treatment, which as surgical in 90 percent of the cases. Preoperative radiotherapy was used in 130 cases. Preoperative radiotherapy was used in 130 cases, matched with 126 untreated cases. Etiologic factors are discussed. The presence and degree of lymph node metastasis are of paramount significance. Indications for elective treatment of the clinically negative neck are discussed in terms of anatomic, logistic and statistical principles. An analysis of failure point toward a continuing effort at combined therapy in this regional disease.
纪念医院头颈科在1965年至1969年最近的5年期间共诊治了1034例口腔和咽表皮样癌。656例此前未经治疗的确诊病例为评估5年治疗结果提供了明确依据，其中90%的病例接受了手术治疗。130例患者采用了术前放疗。130例采用术前放疗的患者与126例未治疗患者进行了匹配。文中讨论了病因因素。淋巴结转移的存在和程度至关重要。根据解剖学、逻辑学和统计学原理讨论了对临床阴性颈部进行选择性治疗的指征。对失败情况的分析表明，针对这种局部疾病仍需继续努力采用联合治疗。
