Blanloeil Y, Baron D, Gazeau M F, Nicolas F
Anesth Analg (Paris). 1980;37(7-8):441-3.
The authors report a D. Penicillamine-induced myasthenia gravis in a patient with rheumatoid arthritis. The disorder was revealed by a postoperative respiratory depression which could be attributed to the aggravation of the neuromuscular blockade by the muscle relaxants. D. Penicillamine-induced myasthenia gravis is now well known. The onset of such an accident after anaesthesia of patient treated with D. Penicillamine is a potential risk. Management of these patients in anaesthesia must be similar to the management of patients with classic myasthenia gravis.
作者报告了1例类风湿关节炎患者因青霉胺诱发重症肌无力。该病症由术后呼吸抑制揭示，这可能归因于肌肉松弛剂加重了神经肌肉阻滞。青霉胺诱发的重症肌无力现已广为人知。接受青霉胺治疗的患者麻醉后发生此类意外是一种潜在风险。这些患者的麻醉管理必须与经典重症肌无力患者的管理相似。
