Rousseau J J, Dieudonne L G
Acta Neurol Belg. 1980 May-Jun;80(3):165-73.
The authors report a case of myasthenia gravis syndrome appearing six months after the start of d-Penicillamine treatment for rheumatoid polyarthritis and disappearing rapidly and definitively after cessation of that treatment. In connection with the case the authors review some forty similar cases in the literature and consider the principal clinical, electrophysiological and immunological aspects. They also discuss the etiopathogenic hypotheses and treatment of this iatrogenic complication.
作者报告了1例重症肌无力综合征,该病例在开始使用青霉胺治疗类风湿性多关节炎6个月后出现,并在停止该治疗后迅速、彻底消失。结合该病例,作者回顾了文献中约40例类似病例,并探讨了主要的临床、电生理和免疫学方面。他们还讨论了这种医源性并发症的病因假说和治疗方法。