Vishnupriya S, Murty J S, Rao M N, Seetha T
Ann Hum Biol. 1980 Mar-Apr;7(2):139-43. doi: 10.1080/03014468000004161.
An attempt is made to enumerate the effects of some factors on hypohaptoglobinaemia in a sample of 389 infants (along with their mothers) who were classified electrophoretically for haptoglobins (Hp). 85 . 5% of infants were Hp 0-0. There was no direct effect of birth-weight on the frequency of Hp 0-0 but there was a significant interaction between maternal haptoglobin type and birth-weight of newborn, showing an excess of 2-2 among mothers of low birth-weight babies, who were mostly Hp 0-0. Some trend towards reduced Hp 0-0 frequency among premature babies was discernible. There was a significant effect of parity on the frequency of detectable haptoglobin patterns among low birth-weight infants. An increase in the frequency of haptoglobin pattern was observed with increase in parity and birth-weight. The distributions of detectable haptoglobin patterns among newborn and mothers were similar. ABO incompatibility, sex, economic status and caste variation did not show any effects on the frequency of Hp 0-0.
对389名婴儿（及其母亲）的样本进行了研究，试图列举某些因素对低结合珠蛋白血症的影响，这些婴儿通过结合珠蛋白（Hp）的电泳进行分类。85.5%的婴儿为Hp 0-0型。出生体重对Hp 0-0型的频率没有直接影响，但母亲结合珠蛋白类型与新生儿出生体重之间存在显著的交互作用，低体重儿的母亲中Hp 2-2型过多，这些母亲大多为Hp 0-0型。早产儿中Hp 0-0型频率有降低的趋势。产次对低体重婴儿中可检测到的结合珠蛋白模式频率有显著影响。随着产次和出生体重的增加，结合珠蛋白模式的频率也有所增加。新生儿和母亲中可检测到的结合珠蛋白模式分布相似。ABO血型不合、性别、经济状况和种姓差异对Hp 0-0型的频率没有任何影响。
