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人视网膜下液中的脂蛋白。

Lipoproteins in human subretinal fluids.

作者信息

Lam K W, van Heuven W A, Ray G S

出版信息

Arch Ophthalmol. 1980 Oct;98(10):1847-9. doi: 10.1001/archopht.1980.01020040699021.

Abstract

The lipids in the subretinal fluid of rhegmatogenous retinal detachment are observed mainly in the albumin position following electrophoresis on agarose film. The lipoprotein in the subchoroidal fluid of the same eye is alpha-lipoprotein. The albumin-like lipoprotein in subretinal fluid has no reaction with the antiserum samples specific to alpha-lipoprotein and beta-lipoprotein. Instead, an apoprotein of serum alpha-lipoprotein with slow electrophoretic mobility was observed in subretinal fluid. Heterogeneous degradation products of serum lipoproteins were seen in the subretinal fluid of exudative retinitis, different from the subretinal fluid of rhegmatogenous retinal detachment and uveal effusion.

摘要

孔源性视网膜脱离患者视网膜下液中的脂质,在琼脂糖膜上电泳后主要出现在白蛋白位置。同一只眼睛脉络膜下液中的脂蛋白为α-脂蛋白。视网膜下液中类似白蛋白的脂蛋白与α-脂蛋白和β-脂蛋白特异性抗血清样本无反应。相反,在视网膜下液中观察到一种电泳迁移率较慢的血清α-脂蛋白载脂蛋白。渗出性视网膜炎患者的视网膜下液中可见血清脂蛋白的异质性降解产物,与孔源性视网膜脱离和葡萄膜渗漏患者的视网膜下液不同。

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