Crompton J L, Iyer P, Begg M W
Aust J Ophthalmol. 1980 Aug;8(3):219-39. doi: 10.1111/j.1442-9071.1980.tb00342.x.
Fundus lesions are said not to be found in direct relationship to rheumatoid arthritis. A vasculitis or retinopathy if present is said to be secondary to concomitant hypertension or due to some connective tissue disease other than rheumatoid arthritis. The case is presented of a 64-year-old female with sero-positive rheumatoid arthritis. During a period of exacerbation of her arthritis she developed anterior ischaemic optic neuropathy (A.I.O.N.) resulting in blindness of one eye, followed two weeks later by a temporary occlusive episode in a cilioretinal arteriole in the other eye. The patient was normotensive and had neither clinical nor immunological evidence of other connective tissue disease. The patient died two months later from cardiac arrhythmia. The autopsy findings confirming posterior ciliary arteritis as the cause of the A.I.O.N. are presented. The subject of rheumatoid vasculitis in relation to the eye is reviewed and immunological mechanisms and investigations discussed.
眼底病变据说是与类风湿性关节炎没有直接关系的。如果存在血管炎或视网膜病变，则被认为是继发于并发的高血压或由类风湿性关节炎以外的某些结缔组织疾病引起的。本文介绍了一例64岁血清阳性类风湿性关节炎女性患者的病例。在她的关节炎加重期间，她患上了前部缺血性视神经病变（A.I.O.N.），导致一只眼睛失明，两周后另一只眼睛的睫状视网膜小动脉出现了一次短暂的闭塞发作。患者血压正常，没有其他结缔组织疾病的临床或免疫学证据。患者两个月后死于心律失常。本文展示了尸检结果，证实睫状后动脉炎是A.I.O.N.的病因。本文回顾了与眼睛相关的类风湿性血管炎主题，并讨论了免疫机制和研究。
