Grosberg S J, Wapnick S
Am J Med Sci. 1978 Nov-Dec;276(3):287-91. doi: 10.1097/00000441-197811000-00005.
Between 1973 to 1976, 12 ascitic cirrhotic patients with a mean plasma creatinine (pCr) of 4.4 +/- 3.0 mg/dl) were treated conservatively. During the same period 11 cirrhotics with ascites (pCr 4.3 +/- 2.8 mg/dl) were treated with LeVeen peritoneal jugular shunt. In the medically treated group mean survival was 2.4 +/- 2.7 weeks after detection of pCr elevation greater than 2.3 mg/dl. The 11 surgical patients with pCr elevation above 2.3 mg/dl survived a mean of 21.8 +/- 34.5 weeks after surgery. Four patients survived more than six months. The LeVeen shunt also resulted in significant weight loss, reduction in blood urea nitrogen (BUN), elevation of serum sodium, and increase of renal clearance of sodium. In appropriately selected patients it reverses the hepato-renal syndrome.
1973年至1976年间，对12例平均血浆肌酐（pCr）为4.4±3.0mg/dl的腹水型肝硬化患者进行了保守治疗。同期，对11例腹水型肝硬化患者（pCr 4.3±2.8mg/dl）进行了LeVeen腹腔颈静脉分流术治疗。在药物治疗组中，检测到pCr升高超过2.3mg/dl后，平均生存期为2.4±2.7周。11例pCr升高超过2.3mg/dl的手术患者术后平均存活21.8±34.5周。4例患者存活超过6个月。LeVeen分流术还导致体重显著减轻、血尿素氮（BUN）降低、血清钠升高以及肾脏钠清除率增加。在适当选择的患者中，它可逆转肝肾综合征。
