Schrek R, Stefani S S
Br J Exp Pathol. 1980 Jun;61(3):256-60.
We measured the effects of X-irradiation plus incubation at elevated temperatures on peripheral blood lymphocytes from normal persons and from patients with chronic lymphocytic leukaemia. Counts of viable lymphocytes were based on morphological characteristics by phase microscopy. Dose-effect curves for X-irradiation were biphasic. The D0S for lymphocytes incubated at 39 and 41 degrees were significantly less than the D0 for 37 degrees. For both normal and leukaemia lymphocytes, X-irradiation was synergistic with hyperthermia at 39 degrees and 41 degrees.
我们测量了X射线照射以及在高温下孵育对正常人和慢性淋巴细胞白血病患者外周血淋巴细胞的影响。活淋巴细胞计数基于相差显微镜下的形态学特征。X射线照射的剂量效应曲线呈双相性。在39℃和41℃孵育的淋巴细胞的D0S显著低于37℃时的D0。对于正常淋巴细胞和白血病淋巴细胞，在39℃和41℃时，X射线照射与热疗具有协同作用。
