De Wolf F, Brosens I, Renaer M
Br J Obstet Gynaecol. 1980 Aug;87(8):678-85. doi: 10.1111/j.1471-0528.1980.tb04601.x.
In five patients with fetal growth retardation in pregnancies with no or only a moderate and transient rise in blood pressure, vascular lesions in the placental bed spiral arteries were found. These lesions are characterized by less well developed physiological morphological changes, by extensive intimal thickening, by fibrinoid degeneration of the media and by acute atherosis. the recurrent fetal growth retardation in these pregnancies may be the first clinical manifestation of underlying reno-vascular disease.
在5例胎儿生长受限的孕妇中，其血压无升高或仅有中度短暂升高，发现胎盘床螺旋动脉有血管病变。这些病变的特征是生理性形态变化发育较差、内膜广泛增厚、中膜纤维蛋白样变性和急性动脉粥样硬化。这些妊娠中反复出现的胎儿生长受限可能是潜在肾血管疾病的首个临床表现。
