Sheppard B L, Bonnar J
Br J Obstet Gynaecol. 1981 Jul;88(7):695-705. doi: 10.1111/j.1471-0528.1981.tb01268.x.
Uteroplacental spiral arteries in placental bed biopsies and placentas form 80 pregnancies were studied by light and electron microscopy; of these 30 were complicated by fatal growth retardation(less than 10th centile) and 45 by hypertension during pregnancy. The physiological changes of the spiral arteries and the vascular pathology present in hypertensive pregnancy and fetal growth retardation were investigated. In normotensive pregnancies complicated by fetal growth retardation, the physiological changes of pregnancy frequently did not extend beyond the decidual segments of the utero-placental arteries. In pregnancies complicated by pre-eclampsia, the physiological changes of pregnancy were not always restricted to the decidual segments of the utero-placental arteries. Atheromatous-like lesions of similar morphology were found in spiral arteries from both normotensive and hypertensive pregnancies complicated by fetal growth retardation. No arteriopathy was found which was specific for pre-eclampsia.
通过光学显微镜和电子显微镜研究了80例妊娠胎盘床活检和胎盘中的子宫胎盘螺旋动脉；其中30例合并胎儿生长受限（低于第10百分位数），45例在孕期合并高血压。研究了螺旋动脉的生理变化以及高血压妊娠和胎儿生长受限中存在的血管病理情况。在合并胎儿生长受限的血压正常的妊娠中，妊娠的生理变化通常不会超出子宫胎盘动脉的蜕膜段。在合并先兆子痫的妊娠中，妊娠的生理变化并不总是局限于子宫胎盘动脉的蜕膜段。在合并胎儿生长受限的血压正常和高血压妊娠的螺旋动脉中发现了形态相似的动脉粥样硬化样病变。未发现先兆子痫特有的动脉病变。
