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[血浆在复苏后状态下的作用机制]

[Mechanism of action of blood plasma in postresuscitation states].

作者信息

Novoderzhkina I S, Molchanova L V, Trubina I E, Sundukov A N

出版信息

Biull Eksp Biol Med. 1980 Sep;90(9):291-3.

PMID:7426728
Abstract

The dogs who suffered 17-minute circulatory arrest induced by electric injury show progressive hemostasis and rheology disorders associated with peripheral and central hemodynamic disturbances. Injection of defibrinated plasma and microdoses of heparin during the first minutes of resuscitation inhibits the generation of thrombin, decreases blood viscosity, and prevents secondary circulation disorders. Hemodynamic stabilizaton is accompanied by the increased oxygen supply and consumption, by acceleration of metabolic disorders correction, which improves the final results of resuscitation.

摘要

因电击伤遭受17分钟循环骤停的犬只出现渐进性止血和流变学紊乱,并伴有外周和中心血流动力学障碍。在复苏的最初几分钟内注射去纤维蛋白血浆和微量肝素可抑制凝血酶的生成,降低血液粘度,并预防继发性循环障碍。血流动力学稳定伴随着氧气供应和消耗的增加,以及代谢紊乱纠正的加速,这改善了复苏的最终结果。

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