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儿童期癫痫:来自全国儿童发展研究的结果。

Epilepsy in childhood: findings from the National Child Development Study.

作者信息

Ross E M, Peckham C S, West P B, Butler N R

出版信息

Br Med J. 1980 Jan 26;280(6209):207-10. doi: 10.1136/bmj.280.6209.207.

DOI:10.1136/bmj.280.6209.207
PMID:7427082
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1600021/
Abstract

By the age of 11 years 1043 children (6.7%) in an unselected national sample had a history of seizures or other episodes of loss of consciousness; 322 (20.8/1000) had a history of febrile convulsions without other epileptic problems. A clear-cut diagnosis of non-febrile epilepsy was established in 64 children (4.1/1000) by the age of 11 on the basis of confirmatory information supplied by family doctors and paediatricians. A further 39 (2.6/1000) were reported as having epilepsy but did not fulfil the study criteria. The progress of 59 of the 64 children with estabished epilepsy was reviewed again when they were aged 16. Of the 37 educated in normal schools eight (22%) had one or more seizures in their 16th year compared with 13 out of 22 (59%) who received special education. A possible cause for epilepsy was found in 17 of the 64 (27%) children, but for the majority there was no obvious reason.

摘要

在一个未经挑选的全国性样本中,到11岁时,1043名儿童(6.7%)有癫痫发作史或其他意识丧失发作史;322名儿童(每1000人中有20.8人)有热性惊厥史且无其他癫痫问题。根据家庭医生和儿科医生提供的确证信息,到11岁时,64名儿童(每1000人中有4.1人)被明确诊断为非热性癫痫。另有39名儿童(每1000人中有2.6人)被报告患有癫痫,但不符合研究标准。64名确诊癫痫的儿童中有59名在16岁时再次接受了病情复查。在37名在普通学校就读的儿童中,8名(22%)在16岁时有一次或多次癫痫发作,而在22名接受特殊教育的儿童中,有13名(59%)在16岁时有癫痫发作。在64名儿童中有17名(27%)找到了癫痫的可能病因,但大多数儿童没有明显原因。

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引用本文的文献

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The Association Between Childhood Seizures and Later Childhood Emotional and Behavioral Problems: Findings From a Nationally Representative Birth Cohort.儿童期癫痫与后期儿童期情绪和行为问题之间的关联:来自全国代表性出生队列的研究结果。
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Epileptic Disord. 2012 Mar;14(1):12-21. doi: 10.1684/epd.2012.0483.
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Co-morbidity of epilepsy in Tanzanian children: a community-based case-control study.坦桑尼亚儿童癫痫共病:一项基于社区的病例对照研究。
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Management and prophylaxis of seizures in children.儿童癫痫的管理和预防。
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The National Children's Study (NCS): establishment and protection of the inferential base.国家儿童研究(NCS):推理基础的建立和保护。
Stat Med. 2010 Jun 15;29(13):1360-7. doi: 10.1002/sim.3635.
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Cognition, academic achievement, language, and psychopathology in pediatric chronic epilepsy: Short-term outcomes.儿童慢性癫痫的认知、学业成绩、语言和精神病理学:短期结局。
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本文引用的文献

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EPILEPSY IN A LONGITUDINAL SURVEY OF 5,000 CHILDREN.对5000名儿童的纵向调查中的癫痫
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Epilepsia. 1975 Jun;16(2):285-93. doi: 10.1111/j.1528-1157.1975.tb06059.x.
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The risk of epilepsy following febrile convulsions.热性惊厥后发生癫痫的风险。
Neurology. 1979 Mar;29(3):297-303. doi: 10.1212/wnl.29.3.297.
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Spontaneous fits after convulsions with fever.发热惊厥后的自发性抽搐。
Arch Dis Child. 1977 Mar;52(3):192-6. doi: 10.1136/adc.52.3.192.