Wallace S J
Arch Dis Child. 1977 Mar;52(3):192-6. doi: 10.1136/adc.52.3.192.
112 of an original sample of 134 children with febrile convulsions were reviewed between 8 years and 9 years 10 months after their initial attack. 17% of those followed up had had at least one spontaneous fit. A significant correlation was found with perinatal abnormalities. 12% had continuing recurrent fits. Persisting grand mal occurred most commonly in lower social class children who had had perinatal abnormalities and continued to have long-term neurological disorders. Psychomotor epilepsy correlated significantly with a prolonged or repeated initial convulsion with unilateral features. It is suggested that the development of grand mal and temporal lobe epilepsies after convulsions with fever are determined by different mechanisms.
在134名热性惊厥儿童的原始样本中,112名在首次发作后的8岁至9岁10个月期间接受了复查。随访的儿童中有17%至少有过一次自发性发作。发现与围产期异常有显著相关性。12%的儿童有持续性复发发作。持续性全身性强直阵挛发作最常见于有围产期异常且仍患有长期神经障碍的社会经济地位较低的儿童。精神运动性癫痫与具有单侧特征的长时间或反复初始惊厥显著相关。有人提出,发热惊厥后全身性强直阵挛发作和颞叶癫痫的发生由不同机制决定。