Gray R E, O'Neal R M
Cancer. 1980 Oct 15;46(8):1868-72. doi: 10.1002/1097-0142(19801015)46:8<1868::aid-cncr2820460827>3.0.co;2-k.
A case of multiple pulmonary scar carcinomas arising in a 53-year-old woman with Hodgkin's disease is reported. Review of the literature reveals that scar carcinoma is generally thought to arise in areas of bronchiolar epithelial proliferation occurring in association with pre-existing lung scars. However, we and others have emphasized that, given the usual gross and histologic picture of scar carcinoma, it is impossible to state with certainty whether the carcinoma arose in response to the scar tissue, or the scar tissue formed consequent to the occurrence of repeated small foci of tumor necrosis. The association of Hodgkin's disease and multiple malignancies is also discussed.
报告了一例发生在一名53岁霍奇金病女性患者身上的多发性肺瘢痕癌病例。文献回顾显示，瘢痕癌通常被认为起源于与既往肺瘢痕相关的细支气管上皮增生区域。然而，我们和其他人都强调，鉴于瘢痕癌通常的大体和组织学表现，无法确定癌是对瘢痕组织的反应而发生，还是由于反复出现的小肿瘤坏死灶而形成瘢痕组织。还讨论了霍奇金病与多种恶性肿瘤的关联。
