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血清锌浓度与心肌梗死的关系。

Zinc concentrations in serum as related to myocardial infarction.

作者信息

Lekakis J, Kalofoutis A

出版信息

Clin Chem. 1980 Nov;26(12):1660-1.

PMID:7428147
Abstract

Zinc concentrations in serum from 99 patients with acute myocardial infarction were correlated with the incidence of further complications and with activities in serum of the "cardiac" enzymes aspartate aminotransferase and lactate dehydrogenase. A significantly subnormal zinc concentration was observed for the patients, the lowest values being observed on the second and third days after infarct, particularly in patients with serious complications. Moreover, a linear correlation was observed between zinc values and enzyme activities until the fourth day after infarct. We conclude that measurement of zinc in the serum may have diagnostic value for acute myocardial infarction, although its prognostic value is still speculative.

摘要

对99例急性心肌梗死患者血清中的锌浓度与进一步并发症的发生率以及血清中“心脏”酶天冬氨酸氨基转移酶和乳酸脱氢酶的活性进行了相关性研究。观察到患者的锌浓度明显低于正常水平,最低值出现在梗死发生后的第二天和第三天,尤其是在有严重并发症的患者中。此外,在梗死发生后的第四天之前,锌值与酶活性之间存在线性相关性。我们得出结论,血清锌的测定可能对急性心肌梗死具有诊断价值,尽管其预后价值仍具有推测性。

相似文献

1
Zinc concentrations in serum as related to myocardial infarction.血清锌浓度与心肌梗死的关系。
Clin Chem. 1980 Nov;26(12):1660-1.
2
[On the diagnostic value of the serum activity of some enzymes in heart infarct].
Z Gesamte Inn Med. 1966 Jun 15;21(12):143-4.
3
[Behavior of glutamic-pyruvic transaminase during the clinical course of acute myocardial infarct].[急性心肌梗死临床过程中谷丙转氨酶的变化]
Arch Sci Med (Torino). 1982 Apr-Jun;139(2):211-4.
4
[Study on the determination of activity of several serum enzymes in the diagnosis of macrofocal myocardial infarct].[几种血清酶活性测定在大片灶性心肌梗死诊断中的研究]
Kardiologiia. 1968 Jun;8(6):82-7.
5
Trace elements in serum from Pakistani patients with acute and chronic ischemic heart disease and hypertension.巴基斯坦急性和慢性缺血性心脏病及高血压患者血清中的微量元素
Clin Chem. 1984 May;30(5):644-8.
6
[Dynamics of the activity of blood serum enzymes and isoenzymes in the early stages of myocardial infarct].[心肌梗死早期血清酶及同工酶活性的动态变化]
Lab Delo. 1980(12):730-3.
7
Diagnostic importance of various enzymatic tests in myocardial infarct.各种酶学检测在心肌梗死中的诊断意义。
Pol Med J. 1970;9(4):798-804.
8
[Dynamics of the activity of blood serum transaminases and lactic dehydrogenase during acute myocardial infarct].[急性心肌梗死期间血清转氨酶和乳酸脱氢酶活性的动态变化]
Kardiologiia. 1968 Jun;8(6):87-90.
9
Study of serum enzymes in myocardial infarction.心肌梗死中血清酶的研究。
Indian Heart J. 1967 Oct;19(4):346-57.
10
Longitudinal changes in serum zinc concentration and distribution after acute myocardial infarction.急性心肌梗死后血清锌浓度及分布的纵向变化
Clin Chim Acta. 1994 Oct 31;230(2):147-56. doi: 10.1016/0009-8981(94)90267-4.

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2
Cation dyshomeostasis and cardiomyocyte necrosis: the Fleckenstein hypothesis revisited.阳离子失衡与心肌细胞坏死:再探弗莱肯斯坦假说。
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3
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Cardiovasc Res. 2009 Feb 15;81(3):500-8. doi: 10.1093/cvr/cvn261. Epub 2008 Oct 3.
4
Tissue 65Zinc translocation in a rat model of chronic aldosteronism.组织65锌在慢性醛固酮增多症大鼠模型中的转运
J Cardiovasc Pharmacol. 2008 Apr;51(4):359-64. doi: 10.1097/FJC.0b013e318165b96e.
5
Another look at zinc.再看锌。
Br Med J (Clin Res Ed). 1981 Apr 4;282(6270):1098-9.