二甲基亚砜对血清渗透压的影响。
Effect of dimethyl sulfoxide on serum osmolality.
作者信息
Runckel D N, Swanson J R
出版信息
Clin Chem. 1980 Nov;26(12):1745-7.
Consecutive values for serum osmolality measured in a patient exceeded (548 mOsm) the previously reported pathological range and, indeed, exceeded that generally considered compatible with life. The patient was receiving large amounts of intravenous dimethyl sulfoxide as part of an experimental protocol to control intracranial pressure resulting from trauma. This compound increases serum osmolality linearly with respect to concentration over the range considered therapeutically significant, 0 to 10 mL/L. The mechanism of its effect on osmolality readings is discussed. It does not interfere with any values for those routine measurements made by continuous-flow (SMAC, Technicon).
一名患者血清渗透压的连续测量值超过了（548毫渗摩尔）先前报道的病理范围，实际上，超过了一般认为与生命相容的范围。该患者正在接受大量静脉注射二甲基亚砜，这是控制创伤引起的颅内压的实验方案的一部分。在治疗上有意义的浓度范围（0至10毫升/升）内，该化合物使血清渗透压随浓度呈线性增加。文中讨论了其对渗透压读数产生影响的机制。它不会干扰连续流动式（SMAC，Technicon）进行的那些常规测量值。
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