Strauss R G, Ghishan F, Mitros F, Ebensberger J R, Kisker C T, Tannous R, Younoszai M K
Dig Dis Sci. 1980 Oct;25(10):798-801. doi: 10.1007/BF01345303.
A patient with common variable immunodeficiency disease is described with severe colitis confined to the rectosigmoid region. Inflammation was extensive in the regions involved and exhibited a character that we believe is most unusual. Inflammation was transmural in the regions involved. Macrophages were the major inflammatory cells, and no granulomas or giant cells were seen. Although the disorder seemed distinct from either ulcerative colitis or Crohn's disease, the colitis responded favorably to oral azulfidine, prednisone, and to steroid enemas.
本文描述了一名患有常见可变免疫缺陷病的患者，其严重结肠炎局限于直肠乙状结肠区域。受累区域的炎症广泛，呈现出一种我们认为非常不寻常的特征。受累区域的炎症是透壁性的。巨噬细胞是主要的炎症细胞，未见肉芽肿或巨细胞。尽管该疾病似乎与溃疡性结肠炎或克罗恩病不同，但这种结肠炎对口服柳氮磺胺吡啶、泼尼松和类固醇灌肠反应良好。
