Diaz-Buxo J A, Hermans P E, Huizenga K A
JAMA. 1975 Sep 15;233(11):1189-91.
Idiopathic late-onset immunoglobulin deficiency in a young man was associated with achlorhydria and a severe intestinal malabsorption syndrome that did not respond to conventional therapy. Combined therapy with high doses of prednisone and tetracycline hydrochloride resulted in weight gain, cessation of diarrhea, improved absorption of water, fat, and vitamin B12, and production of gastric acid after stimulation with histamine. Serum immunoglobulin levels, however, did not increase.
一名年轻男性特发性迟发性免疫球蛋白缺乏症与胃酸缺乏及严重的肠道吸收不良综合征有关，该综合征对传统治疗无反应。大剂量泼尼松和盐酸四环素联合治疗导致体重增加、腹泻停止、水、脂肪和维生素B12吸收改善，以及组胺刺激后胃酸分泌。然而，血清免疫球蛋白水平并未升高。
