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[在快速体外试验中检测人类肿瘤对细胞抑制剂的敏感性(作者译)]

[Testing of sensitivity of human tumours to cytostatics in a rapid in vitro test (author's transl)].

作者信息

Volm M

出版信息

Dtsch Med Wochenschr. 1980 Oct 24;105(43):1493-6. doi: 10.1055/s-2008-1070898.

Abstract

In a cooperative study the predictability of results of cytostatic treatment in patients with tumours using a rapid in vitro test was assessed in 9 university hospitals. Treatment of tumour patients (carcinomas of the ovary, bronchus and various localisations) was performed independently of test results. In vitro tests estimating proliferation-dependent action of cytostatics agree readily with clinical treatment results. Tumours responding badly to cytostatics in the test were also progressive clinically. Results of the rapid in vitro test may thus be used in the decision to perform or withhold cytostatic treatment.

摘要

在一项合作研究中,9家大学医院评估了使用快速体外试验对肿瘤患者进行细胞抑制治疗结果的可预测性。肿瘤患者(卵巢癌、支气管癌及其他不同部位的癌症)的治疗独立于试验结果进行。评估细胞抑制剂增殖依赖性作用的体外试验结果与临床治疗结果高度一致。试验中对细胞抑制剂反应不佳的肿瘤在临床上也呈进展性。因此,快速体外试验的结果可用于决定是否进行细胞抑制治疗。

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