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[在快速体外试验中检测人类肿瘤对细胞抑制剂的敏感性(作者译)]

[Testing of sensitivity of human tumours to cytostatics in a rapid in vitro test (author's transl)].

作者信息

Volm M

出版信息

Dtsch Med Wochenschr. 1980 Oct 24;105(43):1493-6. doi: 10.1055/s-2008-1070898.

DOI:10.1055/s-2008-1070898
PMID:7428654
Abstract

In a cooperative study the predictability of results of cytostatic treatment in patients with tumours using a rapid in vitro test was assessed in 9 university hospitals. Treatment of tumour patients (carcinomas of the ovary, bronchus and various localisations) was performed independently of test results. In vitro tests estimating proliferation-dependent action of cytostatics agree readily with clinical treatment results. Tumours responding badly to cytostatics in the test were also progressive clinically. Results of the rapid in vitro test may thus be used in the decision to perform or withhold cytostatic treatment.

摘要

在一项合作研究中,9家大学医院评估了使用快速体外试验对肿瘤患者进行细胞抑制治疗结果的可预测性。肿瘤患者(卵巢癌、支气管癌及其他不同部位的癌症)的治疗独立于试验结果进行。评估细胞抑制剂增殖依赖性作用的体外试验结果与临床治疗结果高度一致。试验中对细胞抑制剂反应不佳的肿瘤在临床上也呈进展性。因此,快速体外试验的结果可用于决定是否进行细胞抑制治疗。

相似文献

1
[Testing of sensitivity of human tumours to cytostatics in a rapid in vitro test (author's transl)].[在快速体外试验中检测人类肿瘤对细胞抑制剂的敏感性(作者译)]
Dtsch Med Wochenschr. 1980 Oct 24;105(43):1493-6. doi: 10.1055/s-2008-1070898.
2
Use of tritiated nucleotide incorporation for prediction of sensitivity of tumors to cytostatic agents.利用氚标记核苷酸掺入法预测肿瘤对细胞生长抑制剂的敏感性。
Behring Inst Mitt. 1984 May(74):273-84.
3
In vitro short-term test to determine the resistance of human tumors to chemotherapy: Group for Sensitivity Testing of Tumors (KSST).
Cancer. 1981 Nov 15;48(10):2127-35. doi: 10.1002/1097-0142(19811115)48:10<2127::aid-cncr2820481002>3.0.co;2-2.
4
[Testing of solid tumors in childhood for sensitivity against cytostatic agents using an autoradiographic in vitro method (short-term method) (author's transl)].
Arch Geschwulstforsch. 1979;49(3):201-10.
5
[Cytostatic therapy of metastasizing cancers: therapeutic indications and limitations (author's transl)].转移性癌症的细胞抑制疗法:治疗指征与局限性(作者译)
Wien Klin Wochenschr. 1977 Apr 1;89(7):209-15.
6
[In-vitro testing of the sensitivity of mammary carcinoma cells to cytostatic drugs (author's transl)].乳腺癌细胞对细胞抑制药物敏感性的体外试验(作者译)
Dtsch Med Wochenschr. 1975 Oct 3;100(40):2035-42. doi: 10.1055/s-0028-1106497.
7
[Testing of bronchial carcinoma for sensitivity against cytostatics in tissue culture (author's transl)].支气管癌在组织培养中对细胞抑制剂敏感性的检测(作者译)
Arch Geschwulstforsch. 1976;46(1):44-9.
8
[Anticytogram (author's transl)].[抗血细胞图(作者译)]
Quad Sclavo Diagn. 1979 Jun;15 Suppl 1:662-72.
9
[Cytostatics for improvement of clinical tumor surgery].[用于改善临床肿瘤手术的细胞抑制剂]
Zentralbl Chir. 1973 Sep 1;98(35):1233-40.
10
The behaviour of tumour cells of ovarian carcinomata under in vitro conditions and the coincidence with clinical controllability of tumours.卵巢癌肿瘤细胞在体外条件下的行为以及与肿瘤临床可控性的相关性。
Arch Geschwulstforsch. 1981;51(1):133-8.

引用本文的文献

1
Diagnosis and staging of ovarian cancer.卵巢癌的诊断与分期
J Cancer Res Clin Oncol. 1984;107(2):81-8. doi: 10.1007/BF00399376.
2
[Predictive tumor tests in chemotherapeutic treatment concepts of malignant diseases].
Klin Wochenschr. 1983 Jan 17;61(2):77-84. doi: 10.1007/BF01496658.