Ciuffi M
Quad Sclavo Diagn. 1979 Jun;15 Suppl 1:662-72.
In the last few years in an attempt to solve problems of antiblastic chemotherapy, the anticytogram has been developed to test in vitro sensitivity of human neoplastic cell cultures to antiproliferative agents. This method, although not without limitations and criticism, can be considered valid in particular tumor forms where these exists a histological type standardization and possibility of comparison with other known specifically active drugs. It may also be justified in the preclinical pharmacological phase, as the first stage in validity testing of new anticytoproliferative substances.
在过去几年中,为了解决抗恶性肿瘤化疗的问题,已经开发出抗癌细胞图谱来检测人肿瘤细胞培养物对增殖抑制剂的体外敏感性。这种方法虽然并非没有局限性和批评,但在存在组织学类型标准化且可与其他已知的具有特定活性的药物进行比较的特定肿瘤类型中,可以认为是有效的。在临床前药理学阶段,作为新的抗细胞增殖物质有效性测试的第一阶段,它也可能是合理的。