Ciuffi M
Quad Sclavo Diagn. 1979 Jun;15 Suppl 1:662-72.
In the last few years in an attempt to solve problems of antiblastic chemotherapy, the anticytogram has been developed to test in vitro sensitivity of human neoplastic cell cultures to antiproliferative agents. This method, although not without limitations and criticism, can be considered valid in particular tumor forms where these exists a histological type standardization and possibility of comparison with other known specifically active drugs. It may also be justified in the preclinical pharmacological phase, as the first stage in validity testing of new anticytoproliferative substances.