红霉素在人体中的药代动力学。
Erythromycin pharmacokinetics in man.
作者信息
Houin G, Tillement J P, Lhoste F, Rapin M, Soussy C J, Duval J
出版信息
J Int Med Res. 1980;8 Suppl 2:9-14.
PMID:7429008
Abstract
This study shows that high serum concentrations are reached after either ethylsuccinate or lactobionate erythromycin administration. But the short elimination half-life implies repetitive administration to obtain efficacy, the ideal being represented by continuous infusion.
摘要
本研究表明，琥珀酸乙酯红霉素或乳糖酸红霉素给药后均可达到较高的血清浓度。但消除半衰期较短意味着需要重复给药以获得疗效，理想的给药方式是持续输注。
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