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子宫内膜癌的流行病学研究。501例对照试验(作者译)

[An epidemiological study of endometrial cancer. Controlled trial of 501 cases (author's transl)].

作者信息

Ortner A, Klammer J, Sattler K

出版信息

Geburtshilfe Frauenheilkd. 1980 Jul;40(7):624-34. doi: 10.1055/s-2008-1037223.

Abstract

In a retrospective case control study, 501 cases of endometrial cancer were observed from 1955-1975 and an equal number of matched control cases were compared regarding the following parameters: obesity, hypertension, diabetes, age a menopause, parity, age at first and last delivery, age at menarche, menstrual abnormalities, history of prior endometrial biopsies, concomitant ovarian tumours, family history of cancer and history of exposure to radiation. The statistical analysis revealed significant differences regarding the incidence of obesity, hypertension, late menopause, low parity, prior endometrial biopsies and prior exposure to ionizing radiation. However, no significant difference was found between endometrial cancer patients and control patients as to the incidence of diabetes, age at menarche, age at first delivery and family history of cancer. The results of the investigation are discussed and compared with similar reports from the literature.

摘要

在一项回顾性病例对照研究中,观察了1955年至1975年间的501例子宫内膜癌病例,并就以下参数对数量相等的匹配对照病例进行了比较:肥胖、高血压、糖尿病、绝经年龄、产次、首次和末次分娩年龄、初潮年龄、月经异常、既往子宫内膜活检史、伴发卵巢肿瘤、癌症家族史以及辐射暴露史。统计分析显示,在肥胖、高血压、绝经延迟、低产次、既往子宫内膜活检以及既往电离辐射暴露的发生率方面存在显著差异。然而,子宫内膜癌患者与对照患者在糖尿病发生率、初潮年龄、首次分娩年龄以及癌症家族史方面未发现显著差异。对调查结果进行了讨论,并与文献中的类似报告进行了比较。

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