Lau H U, Petschelt E, Poehls H, Pollex G, Unger H H, Zegenhagen V
Arch Geschwulstforsch. 1977;47(1):57-66.
A study of 149 patients with ovarian cancer compared to 149 age-matched women out of the population is analyzed. There were no statistically significant differences in nearly all extragenital and all gynaecological diseases. No differences were found in menstrual history, history of hormonotherapy, age of menarche and menopause, number od nulliparous women, number of deliveries and abortions, radiation exposure, double primaries, blood groups, family history and consumption of nicotine. The findings in this study showed a difference in two variables: There were more women with hypertension and more never married women among the patients with ovarian cancer. It is not possible to define a group of high risk with these findings. It is suggested that endocrine factors influence the onset of ovarian cancer. Therefore these factors more should be taken into consideration in further epidemiological studies.
对149例卵巢癌患者与从人群中选取的149名年龄匹配的女性进行了比较分析。几乎所有生殖器外疾病和所有妇科疾病在统计学上均无显著差异。在月经史、激素治疗史、初潮和绝经年龄、未生育女性数量、分娩和流产次数、辐射暴露、双原发肿瘤、血型、家族史和尼古丁摄入量方面均未发现差异。本研究结果显示两个变量存在差异：卵巢癌患者中高血压女性更多，未婚女性更多。基于这些发现无法确定一组高危人群。提示内分泌因素影响卵巢癌的发病。因此，在进一步的流行病学研究中应更多地考虑这些因素。
